Cargando…

Systematic Review With Meta-analysis: Safety and Effectiveness of Combining Biologics and Small Molecules in Inflammatory Bowel Disease

BACKGROUND: Combining biologics and small molecules could potentially overcome the plateau of drug efficacy in inflammatory bowel disease (IBD). We conducted a systematic review and meta-analysis to assess the safety and effectiveness of dual biologic therapy (DBT), or small molecule combined with a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alayo, Quazim A, Fenster, Marc, Altayar, Osama, Glassner, Kerri L, Llano, Ernesto, Clark-Snustad, Kindra, Patel, Anish, Kwapisz, Lukasz, Yarur, Andres J, Cohen, Benjamin L, Ciorba, Matthew A, Thomas, Deborah, Lee, Scott D, Loftus, Edward V, Fudman, David I, Abraham, Bincy P, Colombel, Jean-Frederic, Deepak, Parakkal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Observations and Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924906/ https://www.ncbi.nlm.nih.gov/pubmed/35310082 http://dx.doi.org/10.1093/crocol/otac002

Ejemplares similares

Nonalcoholic Fatty Liver Disease Is a Risk Factor for Thiopurine Hepatotoxicity in Crohn’s Disease
por: George, Alvin T, et al.
Publicado: (2023)

Case Series: Re-induction of Intravenous, Weight-Based Ustekinumab Is Well Tolerated in Patients With Moderate–Severe Crohn’s Disease
por: Lee, Scott David, et al.
Publicado: (2022)

Favorable Outcomes Combining Vedolizumab With Other Biologics or Tofacitinib for Treatment of Inflammatory Bowel Disease
por: Llano, Ernesto M, et al.
Publicado: (2021)

Clinical Evaluation of Upadacitinib in the Treatment of Adults with Moderately to Severely Active Ulcerative Colitis (UC): Patient Selection and Reported Outcomes
por: Irani, Malcolm, et al.
Publicado: (2023)

Corticosteroids Increase the Risk of Invasive Fungal Infections More Than Tumor Necrosis Factor-Alpha Inhibitors in Patients With Inflammatory Bowel Disease
por: Gregory, Martin H, et al.
Publicado: (2023)

Disease and Treatment Patterns Among Patients With Pouch-related Conditions in a Cohort of Large Tertiary Care Inflammatory Bowel Disease Centers in the United States
por: Barnes, Edward L, et al.
Publicado: (2020)

Biological Therapies for the Management of Enteric Disease: Considerations for the Clinician
por: Saleh, Adam, et al.
Publicado: (2022)

Utility of Intestinal Ultrasound in Clinical Decision-Making for Inflammatory Bowel Disease
por: Saleh, Adam, et al.
Publicado: (2023)

Therapeutic Drug Monitoring in Perianal Fistulizing Crohn’s Disease
por: Zulqarnain, Mir, et al.
Publicado: (2022)

Pustular Rash in Crohn's Patient on Ustekinumab Raises Concern for Drug-Induced Paradoxical Psoriasis
por: Barahimi, Mitra, et al.
Publicado: (2021)

Ustekinumab Exposure in Pregnant Women From Inflammatory Bowel Disease Clinical Trials: Pregnancy Outcomes Through Up To 5 Years in Crohn’s Disease and 2 Years in Ulcerative Colitis
por: Abraham, Bincy P, et al.
Publicado: (2022)

Ustekinumab in treatment of Crohn’s disease: design, development, and potential place in therapy
por: Deepak, Parakkal, et al.
Publicado: (2016)

Novel Concepts for HIV Vaccine Vector Design
por: Alayo, Quazim A., et al.
Publicado: (2017)

CT or MR Enterography to Assess Response During Vedolizumab Therapy for Small Bowel Crohn’s Disease
por: Kwapisz, Lukasz, et al.
Publicado: (2022)

Assessment of Benefit of Advanced Inflammatory Bowel Disease Training: Challenges and Solutions
por: Cushing, Kelly C, et al.
Publicado: (2020)

Dietary Patterns Are Not Associated With Disease Activity Among Patients With Inflammatory Conditions of the Pouch in a Prospective Cohort
por: Barnes, Edward L, et al.
Publicado: (2023)

Treatment Patterns and Standardized Outcome Assessments Among Patients With Inflammatory Conditions of the Pouch in a Prospective Multicenter Registry
por: Barnes, Edward L, et al.
Publicado: (2022)

Noninvasive Targeted Crohn Disease Management by Combining Endoscopic Healing Index and Therapeutic Drug Monitoring
por: Hemperly, Amy, et al.
Publicado: (2021)

Inflammatory Bowel Disease (IBD) pharmacotherapy and the risk of serious infection: a systematic review and network meta-analysis
por: Wheat, Chelle L., et al.
Publicado: (2017)

Worldwide Incidence of Colorectal Cancer, Leukemia, and Lymphoma in Inflammatory Bowel Disease: An Updated Systematic Review and Meta-Analysis
por: Wheat, Chelle L., et al.
Publicado: (2016)

Association Between Vedolizumab Levels, Anti-vedolizumab Antibodies, and Endoscopic Healing Index in a Large Population of Patients with Inflammatory Bowel Diseases
por: Yarur, Andres J., et al.
Publicado: (2020)

Risk Factors for and Frequency of CT Scans, Steroid Use, and Repeat Visits in Inflammatory Bowel Disease Patients Seen at a Single-Center Emergency Department: A Retrospective Cohort Study
por: Euers, Lindsay, et al.
Publicado: (2021)

The Clinical Characteristics and Treatment Outcomes of Concomitant Eosinophilic Esophagitis and Inflammatory Bowel Disease
por: Urquhart, Siri A, et al.
Publicado: (2021)

Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia
por: Briese, Thomas, et al.
Publicado: (2014)

Economic Burden of Fatigue in Inflammatory Bowel Disease
por: Ananthakrishnan, Ashwin N, et al.
Publicado: (2023)

Incidence and Outcomes of Home Parenteral Nutrition in Patients With Crohn Disease in Olmsted County, Minnesota
por: Bakhshi, Zeinab, et al.
Publicado: (2020)

Characterization of Staphylococcal Cassette Chromosome mec Elements from Methicillin-Resistant Staphylococcus pseudintermedius Infections in Australian Animals
por: Worthing, Kate A., et al.
Publicado: (2018)

Bacteriophage populations mirror those of bacterial pathogens at sites of infection
por: Haddock, N. L., et al.
Publicado: (2023)

Network-Based Prediction of Novel CRISPR-Associated Genes in Metagenomes
por: Weissman, Jake L., et al.
Publicado: (2020)

Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization
por: Penaloza-MacMaster, Pablo, et al.
Publicado: (2016)

Predictors, rates, and trends of opioid use disorder among patients hospitalized with chronic pancreatitis
por: Adejumo, Adeyinka Charles, et al.
Publicado: (2021)

Summer Dynamics of Microbial Diversity on a Mountain Glacier
por: Hotaling, Scott, et al.
Publicado: (2022)

Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury
por: LaRovere, Kerri L., et al.
Publicado: (2023)

Complete Genomes of Clade G6 Saccharibacteria Suggest a Divergent Ecological Niche and Lifestyle
por: Baker, Jonathon L.
Publicado: (2021)

Novel Gloeobacterales spp. from Diverse Environments across the Globe
por: Grettenberger, Christen L.
Publicado: (2021)

Extreme C-to-A Hypermutation at a Site of Cytosine-N4 Methylation
por: Cherry, Joshua L.
Publicado: (2021)

Recent Genetic Changes Affecting Enterohemorrhagic Escherichia coli Causing Recurrent Outbreaks
por: Cherry, Joshua L.
Publicado: (2022)

Filamentation Is Associated with Reduced Pathogenicity of Multiple Non-albicans Candida Species
por: Banerjee, Mohua, et al.
Publicado: (2019)

In Vitro Evolution of Cefiderocol Resistance in an NDM-Producing Klebsiella pneumoniae Due to Functional Loss of CirA
por: McElheny, Christi L., et al.
Publicado: (2021)

Direct Observation of the Dynamics of Single-Cell Metabolic Activity during Microbial Diauxic Growth
por: McClelland, H. L. O., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_om6g1e2q0t0cglov038h21jtfj