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Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model
BACKGROUND: Patients with hemophilia have deficiencies in intrinsic coagulation factors and can develop inhibitors that limit the effectiveness of replacement coagulation factors. Marstacimab, a human monoclonal antibody, binds and inhibits the human tissue factor pathway inhibitor. Marstacimab is c...
Autores principales: | Pittman, Debra D., Rakhe, Swapnil, Bowley, Sheryl R., Jasuja, Reema, Barakat, Amey, Murphy, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925002/ https://www.ncbi.nlm.nih.gov/pubmed/35316941 http://dx.doi.org/10.1002/rth2.12679 |
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