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TSLP regulates mitochondrial ROS-induced mitophagy via histone modification in human monocytes

BACKGROUND: Thymic stromal lymphopoietin (TSLP) is a Th2-like cytokine involved in asthma pathogenesis. Excessive reactive oxygen species (ROS) production can lead to airway inflammation, hyperresponsiveness and remodeling. Mitophagy, followed by ROS production, is the selective degradation of mitoc...

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Detalles Bibliográficos
Autores principales:	Lin, Yi-Ching, Lin, Yu-Chih, Tsai, Mei-Lan, Liao, Wei-Ting, Hung, Chih-Hsing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925056/ https://www.ncbi.nlm.nih.gov/pubmed/35292112 http://dx.doi.org/10.1186/s13578-022-00767-w

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