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Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause

Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a functi...

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Autor principal: Goldsmith, Harry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925103/
https://www.ncbi.nlm.nih.gov/pubmed/34958043
http://dx.doi.org/10.3233/JAD-215479
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author Goldsmith, Harry S.
author_facet Goldsmith, Harry S.
author_sort Goldsmith, Harry S.
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description Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a function of normal aging phenomena, less blood results in decreased mitochondria, decreased ATP, and a decrease in neuronal activity, which can eventually lead to Alzheimer’s disease. It has been found that placement of the omentum directly on an Alzheimer’s disease brain can lead to improved cognitive function.
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spelling pubmed-89251032022-03-30 Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause Goldsmith, Harry S. J Alzheimers Dis Editorial Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a function of normal aging phenomena, less blood results in decreased mitochondria, decreased ATP, and a decrease in neuronal activity, which can eventually lead to Alzheimer’s disease. It has been found that placement of the omentum directly on an Alzheimer’s disease brain can lead to improved cognitive function. IOS Press 2022-02-15 /pmc/articles/PMC8925103/ /pubmed/34958043 http://dx.doi.org/10.3233/JAD-215479 Text en © 2022 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editorial
Goldsmith, Harry S.
Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title_full Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title_fullStr Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title_full_unstemmed Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title_short Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
title_sort alzheimer’s disease: a decreased cerebral blood flow to critical intraneuronal elements is the cause
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925103/
https://www.ncbi.nlm.nih.gov/pubmed/34958043
http://dx.doi.org/10.3233/JAD-215479
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