Cargando…
Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause
Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a functi...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925103/ https://www.ncbi.nlm.nih.gov/pubmed/34958043 http://dx.doi.org/10.3233/JAD-215479 |
_version_ | 1784669997631537152 |
---|---|
author | Goldsmith, Harry S. |
author_facet | Goldsmith, Harry S. |
author_sort | Goldsmith, Harry S. |
collection | PubMed |
description | Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a function of normal aging phenomena, less blood results in decreased mitochondria, decreased ATP, and a decrease in neuronal activity, which can eventually lead to Alzheimer’s disease. It has been found that placement of the omentum directly on an Alzheimer’s disease brain can lead to improved cognitive function. |
format | Online Article Text |
id | pubmed-8925103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-89251032022-03-30 Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause Goldsmith, Harry S. J Alzheimers Dis Editorial Normally, an adequate cerebral blood flow arrives at individual cerebral neurons in which the blood flow augments activity of intraneuronal mitochondria, which is the source of intraneuronal ATP, the energy source of cerebral neurons. With a decrease in cerebral blood flow that can occur as a function of normal aging phenomena, less blood results in decreased mitochondria, decreased ATP, and a decrease in neuronal activity, which can eventually lead to Alzheimer’s disease. It has been found that placement of the omentum directly on an Alzheimer’s disease brain can lead to improved cognitive function. IOS Press 2022-02-15 /pmc/articles/PMC8925103/ /pubmed/34958043 http://dx.doi.org/10.3233/JAD-215479 Text en © 2022 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Editorial Goldsmith, Harry S. Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title | Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title_full | Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title_fullStr | Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title_full_unstemmed | Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title_short | Alzheimer’s Disease: A Decreased Cerebral Blood Flow to Critical Intraneuronal Elements Is the Cause |
title_sort | alzheimer’s disease: a decreased cerebral blood flow to critical intraneuronal elements is the cause |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925103/ https://www.ncbi.nlm.nih.gov/pubmed/34958043 http://dx.doi.org/10.3233/JAD-215479 |
work_keys_str_mv | AT goldsmithharrys alzheimersdiseaseadecreasedcerebralbloodflowtocriticalintraneuronalelementsisthecause |