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Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function

BACKGROUND: The Apolipoprotein E (APOE) ɛ4 allele has been linked to increased tau phosphorylation and tangle formation. APOE ɛ4 carriers with elevated tau might be at the higher risk for Alzheimer’s disease (AD) progression. Previous studies showed that tau pathology begins early in areas of the me...

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Detalles Bibliográficos
Autores principales:	Salami, Alireza, Adolfsson, Rolf, Andersson, Micael, Blennow, Kaj, Lundquist, Anders, Adolfsson, Annelie Nordin, Schöll, Michael, Zetterberg, Henrik, Nyberg, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925119/ https://www.ncbi.nlm.nih.gov/pubmed/34924376 http://dx.doi.org/10.3233/JAD-210673

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