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Droplet digital polymerase chain reaction for detection and quantification of cell-free DNA TP53 target somatic mutations in oral cancer

BACKGROUND: TP53 mutation is a driver mutation of oral carcinogenesis. This study investigated cancerous and cell-free DNA (cfDNA) in patients with oral squamous cell carcinoma (OSCC) to detect the target hotspot somatic mutation of TP53. OBJECTIVE: TP53 target hotspot mutations were determined in s...

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Detalles Bibliográficos
Autores principales:	Lin, Li-Han, Cheng, Hui-Wen, Liu, Chung-Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925125/ https://www.ncbi.nlm.nih.gov/pubmed/34366328 http://dx.doi.org/10.3233/CBM-210275

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