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Pentosan polysulfate ameliorates fibrosis and inflammation markers in SV40 MES13 cells by suppressing activation of PI3K/AKT pathway via miR-446a-3p

BACKGROUND: Renal fibrosis is a common outcome of various renal damage, including diabetic nephropathy (DN), the leading cause of end-stage renal disease. Currently, there are no effective therapies for renal fibrosis. The present study aimed to determine whether pentosan polysulphate sodium (PPS),...

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Detalles Bibliográficos
Autores principales:	Xiao, Liangxiang, Chen, Anqun, Gao, Qing, Xu, Bo, Guo, Xiaodan, Guan, Tianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925175/ https://www.ncbi.nlm.nih.gov/pubmed/35291969 http://dx.doi.org/10.1186/s12882-022-02732-8

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