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LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer

BACKGROUND: Histone lysine-specific demethylase 1 (LSD1) expression has been shown to be significantly elevated in gastric cancer (GC) and may be associated with the proliferation and metastasis of GC. It has been reported that LSD1 repressed tumor immunity through programmed cell death 1 ligand 1 (...

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Detalles Bibliográficos
Autores principales:	Shen, Dan-Dan, Pang, Jing-Ru, Bi, Ya-Ping, Zhao, Long-Fei, Li, Yin-Rui, Zhao, Li-Juan, Gao, Ya, Wang, Bo, Wang, Ning, Wei, Liuya, Guo, Huiqin, Liu, Hong-Min, Zheng, Yi-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925194/ https://www.ncbi.nlm.nih.gov/pubmed/35296335 http://dx.doi.org/10.1186/s12943-022-01557-1

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