Design and implementation of a novel pharmacogenetic assay for the identification of the CYP2D6*10 genetic variant

OBJECTIVES: Tamoxifen is considered to be the most widely used adjuvant therapy for hormone receptor positive breast cancer in premenopausal women. However, it is reported that nearly 30% of patients receiving tamoxifen therapy have shown reduced or no benefits. This may be due to the high inter-ind...

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Detalles Bibliográficos
Autores principales: Ranadeva, Nadeeka Dimuthu Kumari, Sirisena, Nirmala Dushyanthi, Wetthasinghe, Tithila Kalum, Noordeen, Nafeesa, Dissanayake, Vajira Harshadeva Weerabaddana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925205/
https://www.ncbi.nlm.nih.gov/pubmed/35296326
http://dx.doi.org/10.1186/s13104-022-05993-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925205/
https://www.ncbi.nlm.nih.gov/pubmed/35296326
http://dx.doi.org/10.1186/s13104-022-05993-6

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