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Design and implementation of a novel pharmacogenetic assay for the identification of the CYP2D6*10 genetic variant
OBJECTIVES: Tamoxifen is considered to be the most widely used adjuvant therapy for hormone receptor positive breast cancer in premenopausal women. However, it is reported that nearly 30% of patients receiving tamoxifen therapy have shown reduced or no benefits. This may be due to the high inter-ind...
Autores principales: | Ranadeva, Nadeeka Dimuthu Kumari, Sirisena, Nirmala Dushyanthi, Wetthasinghe, Tithila Kalum, Noordeen, Nafeesa, Dissanayake, Vajira Harshadeva Weerabaddana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925205/ https://www.ncbi.nlm.nih.gov/pubmed/35296326 http://dx.doi.org/10.1186/s13104-022-05993-6 |
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