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Integrative analysis reveals the functional implications and clinical relevance of pyroptosis in low-grade glioma

Using the Chinese Glioma Genome Atlas (training dataset) and The Cancer Genome Atlas (validation dataset), we found that low-grade gliomas can be divided into two molecular subclasses based on 30 pyroptosis genes. Cluster 1 presented higher immune cell and immune function scores and poorer prognosis...

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Detalles Bibliográficos
Autores principales: Shen, Lin, Li, Yanyan, Li, Na, Zhao, Yajie, Zhou, Qin, Shen, Liangfang, Li, Zhanzhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925295/
https://www.ncbi.nlm.nih.gov/pubmed/35296768
http://dx.doi.org/10.1038/s41598-022-08619-w

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