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J147 Reduces tPA-Induced Brain Hemorrhage in Acute Experimental Stroke in Rats

BACKGROUND AND PURPOSE: J147, a novel neurotrophic compound, was originally developed to treat aging-associated neurological diseases. Based on the broad spectrum of cytoprotective effects exhibited by this compound, we investigated whether J147 has cerebroprotection for acute ischemic stroke and wh...

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Detalles Bibliográficos
Autores principales: Jin, Rong, Wang, Min, Zhong, Wei, Kissinger, Charles R., Villafranca, J. Ernest, Li, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925862/
https://www.ncbi.nlm.nih.gov/pubmed/35309561
http://dx.doi.org/10.3389/fneur.2022.821082