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Nuclear magnetic resonance reveals a two hairpin equilibrium near the 3′-splice site of influenza A segment 7 mRNA that can be shifted by oligonucleotides

Influenza A kills hundreds of thousands of people globally every year and has the potential to generate more severe pandemics. Influenza A's RNA genome and transcriptome provide many potential therapeutic targets. Here, nuclear magnetic resonance (NMR) experiments suggest that one such target c...

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Detalles Bibliográficos
Autores principales: Kauffmann, Andrew D., Kennedy, Scott D., Moss, Walter N., Kierzek, Elzbieta, Kierzek, Ryszard, Turner, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925974/
https://www.ncbi.nlm.nih.gov/pubmed/34983822
http://dx.doi.org/10.1261/rna.078951.121

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