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Nuclear magnetic resonance reveals a two hairpin equilibrium near the 3′-splice site of influenza A segment 7 mRNA that can be shifted by oligonucleotides
Influenza A kills hundreds of thousands of people globally every year and has the potential to generate more severe pandemics. Influenza A's RNA genome and transcriptome provide many potential therapeutic targets. Here, nuclear magnetic resonance (NMR) experiments suggest that one such target c...
Autores principales: | Kauffmann, Andrew D., Kennedy, Scott D., Moss, Walter N., Kierzek, Elzbieta, Kierzek, Ryszard, Turner, Douglas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925974/ https://www.ncbi.nlm.nih.gov/pubmed/34983822 http://dx.doi.org/10.1261/rna.078951.121 |
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