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T-hairpin structure found in the RNA element involved in piRNA biogenesis

PIWI-interacting RNAs (piRNAs) repress transposons to protect the germline genome from DNA damage caused by transposon transposition. In Drosophila, the Traffic jam (Tj) mRNA is consumed to produce piRNA in its 3′-UTR. A cis element located within the 3′-UTR, Tj-cis, is necessary for piRNA biogenesi...

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Detalles Bibliográficos
Autores principales: Takase, Naomi, Otsu, Maina, Hirakata, Shigeki, Ishizu, Hirotsugu, Siomi, Mikiko C., Kawai, Gota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925976/
https://www.ncbi.nlm.nih.gov/pubmed/34987083
http://dx.doi.org/10.1261/rna.078967.121

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