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Synthetic riboswitches for the analysis of tRNA processing by eukaryotic RNase P enzymes

Removal of the 5′-leader region is an essential step in the maturation of tRNA molecules in all domains of life. This reaction is catalyzed by various RNase P activities, ranging from ribonucleoproteins with ribozyme activity to protein-only forms. In Escherichia coli, the efficiency of RNase P-medi...

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Detalles Bibliográficos
Autores principales: Ender, Anna, Grafl, Nadine, Kolberg, Tim, Findeiß, Sven, Stadler, Peter F., Mörl, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925977/
https://www.ncbi.nlm.nih.gov/pubmed/35022261
http://dx.doi.org/10.1261/rna.078814.121