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Synthetic riboswitches for the analysis of tRNA processing by eukaryotic RNase P enzymes
Removal of the 5′-leader region is an essential step in the maturation of tRNA molecules in all domains of life. This reaction is catalyzed by various RNase P activities, ranging from ribonucleoproteins with ribozyme activity to protein-only forms. In Escherichia coli, the efficiency of RNase P-medi...
Autores principales: | Ender, Anna, Grafl, Nadine, Kolberg, Tim, Findeiß, Sven, Stadler, Peter F., Mörl, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925977/ https://www.ncbi.nlm.nih.gov/pubmed/35022261 http://dx.doi.org/10.1261/rna.078814.121 |
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