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Spatial redistribution of neurosecretory vesicles upon stimulation accelerates their directed transport to the plasma membrane
Through the integration of results from an imaging analysis of intracellular trafficking of labelled neurosecretory vesicles in chromaffin cells, we develop a Markov state model to describe their transport and binding kinetics. Our simulation results indicate that a spatial redistribution of neurose...
Autores principales: | Schenk, Elaine B., Meunier, Frederic A., Oelz, Dietmar B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926195/ https://www.ncbi.nlm.nih.gov/pubmed/35294476 http://dx.doi.org/10.1371/journal.pone.0264521 |
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