Comparative therapeutic strategies for preventing aortic rupture in a mouse model of vascular Ehlers-Danlos syndrome

Vascular Ehlers-Danlos syndrome is a rare inherited disorder caused by genetic variants in type III collagen. Its prognosis is especially hampered by unpredictable arterial ruptures and there is no therapeutic consensus. We created a knock-in Col3a1(+/G182R) mouse model and performed a complete gene...

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Detalles Bibliográficos
Autores principales: Legrand, Anne, Guery, Charline, Faugeroux, Julie, Fontaine, Erika, Beugnon, Carole, Gianfermi, Amélie, Loisel-Ferreira, Irmine, Verpont, Marie-Christine, Adham, Salma, Mirault, Tristan, Hadchouel, Juliette, Jeunemaitre, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926273/
https://www.ncbi.nlm.nih.gov/pubmed/35245290
http://dx.doi.org/10.1371/journal.pgen.1010059

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