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Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study

Compelling evidence supports the current international recommendation of at least 150 min/week of leisure-time physical activity (LTPA) during pregnancy. However, the potential relationship between LTPA and birth weight (BW) remains unclear in low- and middle-income countries. The purpose of this st...

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Autores principales: Malta, Maíra B., Neves, Paulo A. R., Lourenço, Bárbara H., Benício, Maria Helena D. A., Werneck, Guilherme L., Castro, Marcia C., Cardoso, Marly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926278/
https://www.ncbi.nlm.nih.gov/pubmed/35294475
http://dx.doi.org/10.1371/journal.pone.0265164
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author Malta, Maíra B.
Neves, Paulo A. R.
Lourenço, Bárbara H.
Benício, Maria Helena D. A.
Werneck, Guilherme L.
Castro, Marcia C.
Cardoso, Marly A.
author_facet Malta, Maíra B.
Neves, Paulo A. R.
Lourenço, Bárbara H.
Benício, Maria Helena D. A.
Werneck, Guilherme L.
Castro, Marcia C.
Cardoso, Marly A.
author_sort Malta, Maíra B.
collection PubMed
description Compelling evidence supports the current international recommendation of at least 150 min/week of leisure-time physical activity (LTPA) during pregnancy. However, the potential relationship between LTPA and birth weight (BW) remains unclear in low- and middle-income countries. The purpose of this study was to examine the association between LTPA during pregnancy and offspring BW in an Amazonian population. Prospective cohort study was carried-out with 500 pregnant women and their offspring followed-up in the MINA-Brazil study, which was conducted in Cruzeiro do Sul, Western Brazilian Amazon. LTPA was assessed in the second (mean 19.6, SD 2.4 weeks) and third (mean 27.8, SD 1.6 weeks) gestational trimesters by a standardised interview and categorised according to the recommended cut-off of at least 150 min/week. We calculated offspring BW z-scores by sex and gestational age. We then explored the effect of LTPA during pregnancy on offspring BW, the association between LTPA and small-for-gestational-age (SGA) or large-for-gestational-age (LGA) births, and the mediating role of excessive and insufficient gestational weight gain (GWG). At least 150 min/week of LTPA during the third gestational trimester was associated with an offspring BW decrease of -0.35 z-score (95% CI: -0.65, -0.05) or -147.9 grams (95% CI: -260.9, -14.8), without increasing the frequency of SGA foetuses either in the second or third gestational trimester (p > 0.05). Excessive GWG mediated the effect of LTPA on the offspring BW (indirect effect = -0.05 z-score [95% CI: -0.10, -0.00] or -34.7 grams (95% CI: -66.1, -3.3]). This mediation effect was not observed for insufficient GWG. LTPA in the third, but not in the second, trimester of pregnancy was inversely associated with offspring BW without increasing the frequency of SGA, an effect that was partly mediated by excessive GWG.
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spelling pubmed-89262782022-03-17 Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study Malta, Maíra B. Neves, Paulo A. R. Lourenço, Bárbara H. Benício, Maria Helena D. A. Werneck, Guilherme L. Castro, Marcia C. Cardoso, Marly A. PLoS One Research Article Compelling evidence supports the current international recommendation of at least 150 min/week of leisure-time physical activity (LTPA) during pregnancy. However, the potential relationship between LTPA and birth weight (BW) remains unclear in low- and middle-income countries. The purpose of this study was to examine the association between LTPA during pregnancy and offspring BW in an Amazonian population. Prospective cohort study was carried-out with 500 pregnant women and their offspring followed-up in the MINA-Brazil study, which was conducted in Cruzeiro do Sul, Western Brazilian Amazon. LTPA was assessed in the second (mean 19.6, SD 2.4 weeks) and third (mean 27.8, SD 1.6 weeks) gestational trimesters by a standardised interview and categorised according to the recommended cut-off of at least 150 min/week. We calculated offspring BW z-scores by sex and gestational age. We then explored the effect of LTPA during pregnancy on offspring BW, the association between LTPA and small-for-gestational-age (SGA) or large-for-gestational-age (LGA) births, and the mediating role of excessive and insufficient gestational weight gain (GWG). At least 150 min/week of LTPA during the third gestational trimester was associated with an offspring BW decrease of -0.35 z-score (95% CI: -0.65, -0.05) or -147.9 grams (95% CI: -260.9, -14.8), without increasing the frequency of SGA foetuses either in the second or third gestational trimester (p > 0.05). Excessive GWG mediated the effect of LTPA on the offspring BW (indirect effect = -0.05 z-score [95% CI: -0.10, -0.00] or -34.7 grams (95% CI: -66.1, -3.3]). This mediation effect was not observed for insufficient GWG. LTPA in the third, but not in the second, trimester of pregnancy was inversely associated with offspring BW without increasing the frequency of SGA, an effect that was partly mediated by excessive GWG. Public Library of Science 2022-03-16 /pmc/articles/PMC8926278/ /pubmed/35294475 http://dx.doi.org/10.1371/journal.pone.0265164 Text en © 2022 Malta et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Malta, Maíra B.
Neves, Paulo A. R.
Lourenço, Bárbara H.
Benício, Maria Helena D. A.
Werneck, Guilherme L.
Castro, Marcia C.
Cardoso, Marly A.
Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title_full Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title_fullStr Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title_full_unstemmed Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title_short Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study
title_sort leisure-time physical activity in amazonian pregnant women and offspring birth weight: a prospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926278/
https://www.ncbi.nlm.nih.gov/pubmed/35294475
http://dx.doi.org/10.1371/journal.pone.0265164
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