HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state

Heat shock factor 1 (HSF1) is well known for its role in the heat shock response (HSR), where it drives a transcriptional program comprising heat shock protein (HSP) genes, and in tumorigenesis, where it drives a program comprising HSPs and many noncanonical target genes that support malignancy. Her...

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Detalles Bibliográficos
Autores principales: Smith, Roger S., Takagishi, Seesha R., Amici, David R., Metz, Kyle, Gayatri, Sitaram, Alasady, Milad J., Wu, Yaqi, Brockway, Sonia, Taiberg, Stephanie L., Khalatyan, Natalia, Taipale, Mikko, Santagata, Sandro, Whitesell, Luke, Lindquist, Susan, Savas, Jeffrey N., Mendillo, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926329/
https://www.ncbi.nlm.nih.gov/pubmed/35294249
http://dx.doi.org/10.1126/sciadv.abj6526

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