Cargando…

Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm

Phyllodes tumor (PT) is a rare benign tumor of the breast with a propensity to recur and metastasize. Ductal carcinoma in situ (DCIS) within PT is an extremely rare finding and is usually diagnosed postoperatively. We present a case of a 36-year-old female with a recurrent lump in her left breast di...

Descripción completa

Detalles Bibliográficos
Autores principales: Brahmachari, Swagata, Kumari, Meena, Sharma, Tanya, Jagtap, Maheshkumar B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926381/
https://www.ncbi.nlm.nih.gov/pubmed/35308191
http://dx.doi.org/10.7759/cureus.23225
_version_ 1784670224623075328
author Brahmachari, Swagata
Kumari, Meena
Sharma, Tanya
Jagtap, Maheshkumar B
author_facet Brahmachari, Swagata
Kumari, Meena
Sharma, Tanya
Jagtap, Maheshkumar B
author_sort Brahmachari, Swagata
collection PubMed
description Phyllodes tumor (PT) is a rare benign tumor of the breast with a propensity to recur and metastasize. Ductal carcinoma in situ (DCIS) within PT is an extremely rare finding and is usually diagnosed postoperatively. We present a case of a 36-year-old female with a recurrent lump in her left breast diagnosed as a benign PT. Preoperatively, aspiration cytology revealed DCIS within the known case of recurrent PT. Emergency left modified radical mastectomy was performed due to an uncontrolled sudden hemorrhage from the tumor. Postoperatively, hormonal therapy was started based on immuno-histopathological findings. DCIS in PT is not encountered frequently and hence no standard management protocol exists for such cases, but when detected by histopathology, the clinical management and prognosis have to undergo a complete change. Preoperative diagnosis and proper individualized management by a multidisciplinary team that ensures clear surgical margins and planned adjuvant therapy play a crucial role in preventing the recurrence of DCIS within PT.
format Online
Article
Text
id pubmed-8926381
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-89263812022-03-18 Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm Brahmachari, Swagata Kumari, Meena Sharma, Tanya Jagtap, Maheshkumar B Cureus Oncology Phyllodes tumor (PT) is a rare benign tumor of the breast with a propensity to recur and metastasize. Ductal carcinoma in situ (DCIS) within PT is an extremely rare finding and is usually diagnosed postoperatively. We present a case of a 36-year-old female with a recurrent lump in her left breast diagnosed as a benign PT. Preoperatively, aspiration cytology revealed DCIS within the known case of recurrent PT. Emergency left modified radical mastectomy was performed due to an uncontrolled sudden hemorrhage from the tumor. Postoperatively, hormonal therapy was started based on immuno-histopathological findings. DCIS in PT is not encountered frequently and hence no standard management protocol exists for such cases, but when detected by histopathology, the clinical management and prognosis have to undergo a complete change. Preoperative diagnosis and proper individualized management by a multidisciplinary team that ensures clear surgical margins and planned adjuvant therapy play a crucial role in preventing the recurrence of DCIS within PT. Cureus 2022-03-16 /pmc/articles/PMC8926381/ /pubmed/35308191 http://dx.doi.org/10.7759/cureus.23225 Text en Copyright © 2022, Brahmachari et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Brahmachari, Swagata
Kumari, Meena
Sharma, Tanya
Jagtap, Maheshkumar B
Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title_full Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title_fullStr Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title_full_unstemmed Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title_short Synchronous Luminal A Ductal Carcinoma In Situ in a Recurrent Benign Phyllodes Tumor Diagnosed Preoperatively: An Unusual Presentation of a Rare Neoplasm
title_sort synchronous luminal a ductal carcinoma in situ in a recurrent benign phyllodes tumor diagnosed preoperatively: an unusual presentation of a rare neoplasm
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926381/
https://www.ncbi.nlm.nih.gov/pubmed/35308191
http://dx.doi.org/10.7759/cureus.23225
work_keys_str_mv AT brahmachariswagata synchronousluminalaductalcarcinomainsituinarecurrentbenignphyllodestumordiagnosedpreoperativelyanunusualpresentationofarareneoplasm
AT kumarimeena synchronousluminalaductalcarcinomainsituinarecurrentbenignphyllodestumordiagnosedpreoperativelyanunusualpresentationofarareneoplasm
AT sharmatanya synchronousluminalaductalcarcinomainsituinarecurrentbenignphyllodestumordiagnosedpreoperativelyanunusualpresentationofarareneoplasm
AT jagtapmaheshkumarb synchronousluminalaductalcarcinomainsituinarecurrentbenignphyllodestumordiagnosedpreoperativelyanunusualpresentationofarareneoplasm