Monitoring of Circulating CAR T Cells: Validation of a Flow Cytometric Assay, Cellular Kinetics, and Phenotype Analysis Following Tisagenlecleucel

Chimeric antigen receptor (CAR) T cell therapy is a potent new treatment option for relapsed or refractory hematologic malignancies. As the monitoring of CAR T cell kinetics can provide insights into the activity of the therapy, appropriate CAR T cell detection methods are essential. Here, we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Peinelt, Andreas, Bremm, Melanie, Kreyenberg, Hermann, Cappel, Claudia, Banisharif-Dehkordi, Julia, Erben, Stephanie, Rettinger, Eva, Jarisch, Andrea, Meisel, Roland, Schlegel, Paul-Gerhardt, Beck, Olaf, Bug, Gesine, Klusmann, Jan-Henning, Klingebiel, Thomas, Huenecke, Sabine, Bader, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926389/
https://www.ncbi.nlm.nih.gov/pubmed/35309367
http://dx.doi.org/10.3389/fimmu.2022.830773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926389/
https://www.ncbi.nlm.nih.gov/pubmed/35309367
http://dx.doi.org/10.3389/fimmu.2022.830773

Ejemplares similares