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Statistical Sequential Experimentation: Preliminary Mixed Factorial Design, I-Optimal Mixture Design Then Finally Novel Design Space Expansion for Optimization of Tazarotene Cubosomes

OBJECTIVE: This study aims to illustrate the potential of sequential experimentation for statistically scientific based optimization of Tazarotene (TAZA) cubosomes. METHODS: Hot melt emulsification method was used for cubosomes preparation. A preliminary (3.2) mixed factorial design (MFD) was conduc...

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Detalles Bibliográficos
Autores principales:	Hegazy, Doaa, Tag, Randa, Habib, Basant Ahmed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926415/ https://www.ncbi.nlm.nih.gov/pubmed/35309964 http://dx.doi.org/10.2147/IJN.S337130

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