Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep Deprivation

Sleep deprivation (SD) induces systemic inflammation that promotes neuronal pyroptosis. The purpose of this study was to investigate the effect of an antioxidant modafinil on neuronal pyroptosis and cognitive decline following SD. Using a mouse model of SD, we found that modafinil improved learning...

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Detalles Bibliográficos
Autores principales: Xiong, Xiangyang, Zuo, Yan, Cheng, Lu, Yin, Zhenyu, Hu, Tianpeng, Guo, Mengtian, Han, Zhaoli, Ge, Xintong, Li, Wenzhu, Wang, Yan, Wang, Dong, Wang, Conglin, Zhang, Lan, Zhang, Yaodan, Liu, Qiang, Chen, Fanglian, Lei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927040/
https://www.ncbi.nlm.nih.gov/pubmed/35310096
http://dx.doi.org/10.3389/fnins.2022.816752

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