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Treatment with Soluble Activin Type IIB Receptor Ameliorates Ovariectomy-Induced Bone Loss and Fat Gain in Mice
INTRODUCTION: In postmenopausal osteoporosis, hormonal changes lead to increased bone turnover and metabolic alterations including increased fat mass and insulin resistance. Activin type IIB receptors bind several growth factors of the TGF-β superfamily and have been demonstrated to increase muscle...
Autores principales: | Puolakkainen, Tero, Rummukainen, Petri, Pihala-Nieminen, Vappu, Ritvos, Olli, Savontaus, Eriika, Kiviranta, Riku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927044/ https://www.ncbi.nlm.nih.gov/pubmed/35024891 http://dx.doi.org/10.1007/s00223-021-00934-0 |
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