Whole Transcriptome Mapping Identifies an Immune- and Metabolism-Related Non-coding RNA Landscape Remodeled by Mechanical Stress in IL-1β-Induced Rat OA-like Chondrocytes

Background: Osteoarthritis (OA) is a common degenerative joint disease. The aims of this study are to explore the effects of mechanical stress on whole transcriptome landscape and to identify a non-coding transcriptome signature of mechanical stress. Methods: Next-generation RNA sequencing (RNA-seq)...

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Detalles Bibliográficos
Autores principales: Zhang, Jiaming, Hao, Xiaoxia, Chi, Ruimin, Liu, Jiawei, Shang, Xingru, Deng, Xiaofeng, Qi, Jun, Xu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927047/
https://www.ncbi.nlm.nih.gov/pubmed/35309149
http://dx.doi.org/10.3389/fgene.2022.821508

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