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IRF4b and IRF8 Negatively Regulate RLR-Mediated NF-κB Signaling by Targeting MITA for Degradation in Teleost Fish

Mediator of IRF3 activation (MITA) is a significant signal adaptor in the retinoic acid-inducible gene-I like receptor (RLR) signaling pathway and plays an important role in the innate immune system. As a transcription factor, nuclear factor kappa B (NF-κB) can be available in many signaling pathway...

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Detalles Bibliográficos
Autores principales:	Yan, Xiaolong, Zhao, Xueyan, Zhou, Ming, Sun, Yuena, Xu, Tianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927078/ https://www.ncbi.nlm.nih.gov/pubmed/35309315 http://dx.doi.org/10.3389/fimmu.2022.858179

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