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Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients
Evidence regarding the recurrence of diverticulitis is limited in Asian patients. This study aims to investigate recurrence rates and identify predictive factors for the recurrence of diverticulitis following successful nonoperative treatment in Asian patients. A multicenter, retrospective cohort st...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927129/ https://www.ncbi.nlm.nih.gov/pubmed/35296787 http://dx.doi.org/10.1038/s41598-022-08708-w |
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author | Sung, Chih-Wei Liu, Kao-Lang Wang, Hsiu-Po Chen, I.-Chung Huang, Edward Pei-Chuan Lien, Wan-Ching Huang, Chien-Hua |
author_facet | Sung, Chih-Wei Liu, Kao-Lang Wang, Hsiu-Po Chen, I.-Chung Huang, Edward Pei-Chuan Lien, Wan-Ching Huang, Chien-Hua |
author_sort | Sung, Chih-Wei |
collection | PubMed |
description | Evidence regarding the recurrence of diverticulitis is limited in Asian patients. This study aims to investigate recurrence rates and identify predictive factors for the recurrence of diverticulitis following successful nonoperative treatment in Asian patients. A multicenter, retrospective cohort study was conducted between 2012 and 2018. Adult patients with computed tomography (CT)-proven colonic diverticulitis were included. The primary outcome was the recurrence of diverticulitis, which was defined as another episode of occurrence of the infection after index hospital stay. Cumulative recurrence rates were calculated using the Kaplan–Meier method. Cox regression models were employed to identify parameters that significantly and independently predicted recurrence. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated. A total of 929 patients were included. Diverticulitis in the cecum/ascending occurred in 675 (72.6%) patients. The average follow-up period was 651 days. Recurrence was observed in 115 (12.4%) patients and most significantly observed in patients with sigmoid diverticulitis (HR, 2.24; 95% CIs 1.59–3.97), followed by those with descending colon diverticulitis (HR, 1.92; 95% CIs 1.17–3.25). Although most of the Asian patients had right-sided colonic diverticulitis, those with sigmoid diverticulitis had the highest risk of recurrence. |
format | Online Article Text |
id | pubmed-8927129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-89271292022-03-17 Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients Sung, Chih-Wei Liu, Kao-Lang Wang, Hsiu-Po Chen, I.-Chung Huang, Edward Pei-Chuan Lien, Wan-Ching Huang, Chien-Hua Sci Rep Article Evidence regarding the recurrence of diverticulitis is limited in Asian patients. This study aims to investigate recurrence rates and identify predictive factors for the recurrence of diverticulitis following successful nonoperative treatment in Asian patients. A multicenter, retrospective cohort study was conducted between 2012 and 2018. Adult patients with computed tomography (CT)-proven colonic diverticulitis were included. The primary outcome was the recurrence of diverticulitis, which was defined as another episode of occurrence of the infection after index hospital stay. Cumulative recurrence rates were calculated using the Kaplan–Meier method. Cox regression models were employed to identify parameters that significantly and independently predicted recurrence. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated. A total of 929 patients were included. Diverticulitis in the cecum/ascending occurred in 675 (72.6%) patients. The average follow-up period was 651 days. Recurrence was observed in 115 (12.4%) patients and most significantly observed in patients with sigmoid diverticulitis (HR, 2.24; 95% CIs 1.59–3.97), followed by those with descending colon diverticulitis (HR, 1.92; 95% CIs 1.17–3.25). Although most of the Asian patients had right-sided colonic diverticulitis, those with sigmoid diverticulitis had the highest risk of recurrence. Nature Publishing Group UK 2022-03-16 /pmc/articles/PMC8927129/ /pubmed/35296787 http://dx.doi.org/10.1038/s41598-022-08708-w Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Sung, Chih-Wei Liu, Kao-Lang Wang, Hsiu-Po Chen, I.-Chung Huang, Edward Pei-Chuan Lien, Wan-Ching Huang, Chien-Hua Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title_full | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title_fullStr | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title_full_unstemmed | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title_short | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients |
title_sort | colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in asian patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927129/ https://www.ncbi.nlm.nih.gov/pubmed/35296787 http://dx.doi.org/10.1038/s41598-022-08708-w |
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