Transcriptional control of retinal ganglion cell death after axonal injury

Injury to the axons of retinal ganglion cells (RGCs) is a key pathological event in glaucomatous neurodegeneration. The transcription factors JUN (the target of the c-Jun N-terminal kinases, JNKs) and DDIT3/CHOP (a mediator of the endoplasmic reticulum stress response) have been shown to control the...

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Detalles Bibliográficos
Autores principales: Syc-Mazurek, Stephanie B., Yang, Hongtian Stanley, Marola, Olivia J., Howell, Gareth R., Libby, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927149/
https://www.ncbi.nlm.nih.gov/pubmed/35296661
http://dx.doi.org/10.1038/s41419-022-04666-3

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