Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Cellular plasticity contributes to intra-tumoral heterogeneity and phenotype switching, which enable adaptation to metastatic microenvironments and resistance to therapies. Mechanisms underlying tumor cell plasticity remain poorly understood. SOX10, a neural crest lineage transcription factor, is he...

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Detalles Bibliográficos
Autores principales: Capparelli, Claudia, Purwin, Timothy J., Glasheen, McKenna, Caksa, Signe, Tiago, Manoela, Wilski, Nicole, Pomante, Danielle, Rosenbaum, Sheera, Nguyen, Mai Q., Cai, Weijia, Franco-Barraza, Janusz, Zheng, Richard, Kumar, Gaurav, Chervoneva, Inna, Shimada, Ayako, Rebecca, Vito W., Snook, Adam E., Hookim, Kim, Xu, Xiaowei, Cukierman, Edna, Herlyn, Meenhard, Aplin, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927161/
https://www.ncbi.nlm.nih.gov/pubmed/35296667
http://dx.doi.org/10.1038/s41467-022-28801-y

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