Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood–Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight Junction Protein Reduction in Rat Stroke Model

Blood–brain barrier (BBB) dysfunction causing edema and hemorrhagic transformation is one of the pathophysiological characteristics of stroke. Protection of BBB integrity has shown great potential in improving stroke outcome. Here, we assessed the efficacy of exosomes extracted from healthy rat seru...

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Detalles Bibliográficos
Autores principales: Huang, Lin-Yan, Song, Jin-Xiu, Cai, Heng, Wang, Pei-Pei, Yin, Qi-Long, Zhang, Yi-De, Chen, Jie, Li, Ming, Song, Jia-Jia, Wang, Yan-Ling, Luo, Lan, Wang, Wan, Qi, Su-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927286/
https://www.ncbi.nlm.nih.gov/pubmed/35308117
http://dx.doi.org/10.3389/fncel.2022.841544

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