Cargando…

Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis

Cancer cells display phenotypic equilibrium between the stem-like and differentiated states during neoplastic homeostasis. The functional and mechanistic implications of this subpopulation plasticity remain largely unknown. Herein, it is demonstrated that the breast cancer stem cell (BCSC) secretome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Mingming, Zhang, Xiao, Zhang, Weijie, Chiou, Yi Shiou, Qian, Wenchang, Liu, Xiangtian, Zhang, Min, Yan, Hong, Li, Shilan, Li, Tao, Han, Xinghua, Qian, Pengxu, Liu, Suling, Pan, Yueyin, Lobie, Peter E., Zhu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927306/ https://www.ncbi.nlm.nih.gov/pubmed/35296660 http://dx.doi.org/10.1038/s41467-022-29018-9

Ejemplares similares

Paracrine secretion of IL8 by breast cancer stem cells promotes therapeutic resistance and metastasis of the bulk tumor cells
por: Wu, Mingming, et al.
Publicado: (2023)

Linc00668 Promotes Invasion and Stem Cell-Like Properties of Breast Cancer Cells by Interaction With SND1
por: Qian, Wenchang, et al.
Publicado: (2020)

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor
por: Liu, Ying, et al.
Publicado: (2015)

Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
por: Tan, Sheng, et al.
Publicado: (2014)

Sigma‐1 receptor protects against ferroptosis in hepatocellular carcinoma cells
por: Bai, Tao, et al.
Publicado: (2019)

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review
por: Lei, Pengxu, et al.
Publicado: (2019)

Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis
por: Zhu, Yong, et al.
Publicado: (2019)

Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
por: Zhang, Min, et al.
Publicado: (2015)

Small noncoding RNAs play superior roles in maintaining hematopoietic stem cell homeostasis
por: Wang, Hui, et al.
Publicado: (2022)

CCAR1 5′ UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance
por: Li, Gaopeng, et al.
Publicado: (2016)

Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma
por: Kong, Xiangjun, et al.
Publicado: (2016)

Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis
por: Huang, Yongzhou, et al.
Publicado: (2023)

Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1
por: Kong, Na, et al.
Publicado: (2021)

Editorial: Characteristics and behaviors of hematopoietic stem cells and leukemia stem cells in hematologic malignancies
por: Zhang, Haojian, et al.
Publicado: (2022)

ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma
por: Banerjee, Arindam, et al.
Publicado: (2011)

Regulation of iron metabolism and ferroptosis in cancer stem cells
por: Wang, Hailiang, et al.
Publicado: (2023)

Machine learning models based on immunological genes to predict the response to neoadjuvant therapy in breast cancer patients
por: Chen, Jian, et al.
Publicado: (2022)

Lymph protects metastasizing melanoma cells from ferroptosis
por: Ubellacker, Jessalyn M., et al.
Publicado: (2020)

Construction of a prognostic model for non-small-cell lung cancer based on ferroptosis-related genes
por: Han, Ke, et al.
Publicado: (2021)

Ferroptosis of Endothelial Cells in Vascular Diseases
por: Zhang, Hanxu, et al.
Publicado: (2022)

Lipid metabolism in ferroptosis and ferroptosis-based cancer therapy
por: Sun, Yonghao, et al.
Publicado: (2022)

Pan-cancer and single-cell analysis reveals FAM83D expression as a cancer prognostic biomarker
por: Yu, Haiyang, et al.
Publicado: (2022)

MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression
por: Kong, Xiangjun, et al.
Publicado: (2012)

Small but strong: Pivotal roles and potential applications of snoRNAs in hematopoietic malignancies
por: Dong, Jian, et al.
Publicado: (2022)

Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
por: Tong, Xuhui, et al.
Publicado: (2022)

Corosolic acid sensitizes ferroptosis by upregulating HERPUD1 in liver cancer cells
por: Peng, Yingxiu, et al.
Publicado: (2022)

Role of ferroptosis and ferroptosis-related non-coding RNAs in the occurrence and development of gastric cancer
por: Lu, Ling, et al.
Publicado: (2022)

Glutamine deprivation induces ferroptosis in pancreatic cancer cells: Glutamine deprivation induces pancreatic cancer ferroptosis
por: Xiao, Zhiwen, et al.
Publicado: (2023)

The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression
por: Wu, Yuqing, et al.
Publicado: (2020)

Nimotuzumab Combined with Chemotherapy is a Promising Treatment for Locally Advanced and Metastatic Esophageal Cancer
por: Han, Xinghua, et al.
Publicado: (2017)

Targeting Breast Cancer Stem Cells
por: Zhang, Lu, et al.
Publicado: (2023)

Insights Into Ferroptosis, a Novel Target for the Therapy of Cancer
por: Wang, Hong-Tao, et al.
Publicado: (2022)

Construction and validation of a ferroptosis-related long noncoding RNA signature in clear cell renal cell carcinoma
por: Zhu, Zhenpeng, et al.
Publicado: (2022)

Performance assessment of sample-specific network control methods for bulk and single-cell biological data analysis
por: Guo, Wei-Feng, et al.
Publicado: (2021)

Ruscogenin induces ferroptosis in pancreatic cancer cells
por: Song, Zhiwang, et al.
Publicado: (2020)

Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis
por: Zhu, Zeen, et al.
Publicado: (2022)

Curcumin suppresses tumorigenesis by ferroptosis in breast cancer
por: Cao, Xuelei, et al.
Publicado: (2022)

Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling
por: Zhang, Weifan, et al.
Publicado: (2022)

Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells
por: Zhang, Haiyang, et al.
Publicado: (2021)

The PTBP1‑NCOA4 axis promotes ferroptosis in liver cancer cells
por: Yang, Hao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sab51rkgduj0j1js23jl80b1um