Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca(2+) release in cancer cells

Mitochondria are the major organelles in sensing cellular stress and inducing the response for cell survival. Mitochondrial Lon has been identified as an important stress protein involved in regulating proliferation, metastasis, and apoptosis in cancer cells. However, the mechanism of retrograde sig...

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Detalles Bibliográficos
Autores principales: Tangeda, Vidhya, Lo, Yu Kang, Babuharisankar, Ananth Ponneri, Chou, Han-Yu, Kuo, Cheng-Liang, Kao, Yung-Hsi, Lee, Alan Yueh-Luen, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927349/
https://www.ncbi.nlm.nih.gov/pubmed/35296653
http://dx.doi.org/10.1038/s41419-022-04668-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927349/
https://www.ncbi.nlm.nih.gov/pubmed/35296653
http://dx.doi.org/10.1038/s41419-022-04668-1

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