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Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming

BACKGROUND: Thymidine kinase 1 (TK1) is a cell cycle-dependent kinase that catalyzes the addition of a gamma-phosphate group to thymidine. The protumorigenic role of TK1 has been reported in various malignancies. However, the role of TK1 in skin cutaneous melanoma (SKCM) remains unclear. This study...

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Detalles Bibliográficos
Autores principales:	Zuo, Sipeng, Wang, Huixue, Li, Lin, Pan, Hui, Lu, Linna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927676/ https://www.ncbi.nlm.nih.gov/pubmed/35311151 http://dx.doi.org/10.3389/fonc.2022.802807

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