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A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis

INTRODUCTION AND IMPORTANCE: Esophageal TB is a relatively uncommon condition. Mostly, the esophagus can be affected by tuberculosis through direct spread or from mediastinal nodes (rarely from the lungs or bloodstream). The most common symptom is dysphagia, and the diagnosis is confirmed by histolo...

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Autores principales: Salad, Najib Mohamed, Ali, Ismail A., Mohamed, Yahye Garad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927689/
https://www.ncbi.nlm.nih.gov/pubmed/35298984
http://dx.doi.org/10.1016/j.ijscr.2022.106883
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author Salad, Najib Mohamed
Ali, Ismail A.
Mohamed, Yahye Garad
author_facet Salad, Najib Mohamed
Ali, Ismail A.
Mohamed, Yahye Garad
author_sort Salad, Najib Mohamed
collection PubMed
description INTRODUCTION AND IMPORTANCE: Esophageal TB is a relatively uncommon condition. Mostly, the esophagus can be affected by tuberculosis through direct spread or from mediastinal nodes (rarely from the lungs or bloodstream). The most common symptom is dysphagia, and the diagnosis is confirmed by histology. If left untreated, esophageal tuberculosis can result in bleeding, perforation, fistula formation, aspiration pneumonia, lethal hematemesis, traction diverticula, and esophageal strictures. CASE PRESENTATION: This is a rare case report of an esophageal fistula caused by tuberculosis in a patient presenting with a cough on eating and weight loss. The patient was subjected to upper gastrointestinal endoscopy, which revealed a cervical esophagus fistula 20 cm from the upper central incisors. Histopathology revealed inflammatory lesions with epithelioid granulomas (granulomatous disease). A mycobacterium sputum examination was performed; the smear was negative. The patient was managed conservatively with anti-tuberculosis treatment (ATT). A follow-up endoscopy after two months revealed that the fistula was closed and clinically improved. CLINICAL DISCUSSION: The quick clearance of contaminated sputum by coordinated peristalsis, paired with upright posture and an intact lower esophageal sphincter, limits the organism's exposure to the esophagus. CONCLUSION: Despite the disease's rarity, if not delayed, it can be efficiently managed with ATT to avoid major complications like esophageal perforation, which necessitates surgery.
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spelling pubmed-89276892022-03-18 A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis Salad, Najib Mohamed Ali, Ismail A. Mohamed, Yahye Garad Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Esophageal TB is a relatively uncommon condition. Mostly, the esophagus can be affected by tuberculosis through direct spread or from mediastinal nodes (rarely from the lungs or bloodstream). The most common symptom is dysphagia, and the diagnosis is confirmed by histology. If left untreated, esophageal tuberculosis can result in bleeding, perforation, fistula formation, aspiration pneumonia, lethal hematemesis, traction diverticula, and esophageal strictures. CASE PRESENTATION: This is a rare case report of an esophageal fistula caused by tuberculosis in a patient presenting with a cough on eating and weight loss. The patient was subjected to upper gastrointestinal endoscopy, which revealed a cervical esophagus fistula 20 cm from the upper central incisors. Histopathology revealed inflammatory lesions with epithelioid granulomas (granulomatous disease). A mycobacterium sputum examination was performed; the smear was negative. The patient was managed conservatively with anti-tuberculosis treatment (ATT). A follow-up endoscopy after two months revealed that the fistula was closed and clinically improved. CLINICAL DISCUSSION: The quick clearance of contaminated sputum by coordinated peristalsis, paired with upright posture and an intact lower esophageal sphincter, limits the organism's exposure to the esophagus. CONCLUSION: Despite the disease's rarity, if not delayed, it can be efficiently managed with ATT to avoid major complications like esophageal perforation, which necessitates surgery. Elsevier 2022-02-25 /pmc/articles/PMC8927689/ /pubmed/35298984 http://dx.doi.org/10.1016/j.ijscr.2022.106883 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Salad, Najib Mohamed
Ali, Ismail A.
Mohamed, Yahye Garad
A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title_full A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title_fullStr A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title_full_unstemmed A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title_short A case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
title_sort case report of medically managed esophageal fistula due to complicated esophageal tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927689/
https://www.ncbi.nlm.nih.gov/pubmed/35298984
http://dx.doi.org/10.1016/j.ijscr.2022.106883
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