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Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis

As one of the cornerstones of clinical cardiovascular disease treatment, statins have an extensive range of applications. However, statins commonly used have side reactions, especially muscle-related symptoms (SAMS), such as muscle weakness, pain, cramps, and severe condition of rhabdomyolysis. This...

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Detalles Bibliográficos
Autores principales:	Zhang, Qi, Qu, Hang, Chen, Yinghui, Luo, Xueyang, Chen, Chong, Xiao, Bing, Ding, Xiaowei, Zhao, Pengjun, Lu, Yanan, Chen, Alex F., Yu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927716/ https://www.ncbi.nlm.nih.gov/pubmed/35309902 http://dx.doi.org/10.3389/fcell.2022.806081

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