Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant

Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (card...

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Detalles Bibliográficos
Autores principales: van der Velden, Fabian J. S., van Delft, Frederik, Owens, Stephen, Llevadias, Judit, McKean, Michael, Pulford, Lindsey, Taha, Yusri, Williamson, Grace, Campbell-Hewson, Quentin, Hambleton, Sophie, Payne, Rebecca, Duncan, Christopher, Johnston, Catriona, Spegarova, Jarmila, Emonts, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927762/
https://www.ncbi.nlm.nih.gov/pubmed/35311038
http://dx.doi.org/10.3389/fped.2022.809061
Descripción
Sumario:Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.

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