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Brain microvascular endothelial cells derived from human induced pluripotent stem cells as in vitro model for assessing blood-brain barrier transferrin receptor-mediated transcytosis
The blood-brain barrier (BBB), a selective barrier formed by brain microvascular endothelial cells (BMEC), represents a major challenge for the efficient accumulation of pharmaceutical drugs into the brain. The receptor-mediated transcytosis (RMT) has recently gained increasing interest for pharmace...
Autores principales: | Piantino, Marie, Louis, Fiona, Shigemoto-Mogami, Yukari, Kitamura, Kimiko, Sato, Kaoru, Yamaguchi, Tomoko, Kawabata, Kenji, Yamamoto, Syunsuke, Iwasaki, Shinji, Hirabayashi, Hideki, Matsusaki, Michiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927846/ https://www.ncbi.nlm.nih.gov/pubmed/35308041 http://dx.doi.org/10.1016/j.mtbio.2022.100232 |
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