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Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING

The tumor-associated macrophage (TAM) serves as an immunosuppressive agent in the malignant tumor microenvironment, facilitating the development and metastasis of lung cancer. The photodynamic effect destabilizes cellular homeostasis owing to the generation of reactive oxygen species (ROS), resultin...

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Detalles Bibliográficos
Autores principales:	Yu, Ting-Ting, Han, Ning, Li, Liu-Gen, Peng, Xing-Chun, Li, Qi-Rui, Xu, Hua-Zhen, Wang, Xi-Yong, Yang, Zi-Yi, Chen, Xiao, Wang, Mei-Fang, Li, Tong-Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927874/ https://www.ncbi.nlm.nih.gov/pubmed/35308251 http://dx.doi.org/10.3389/fphar.2022.837784

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