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Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes

Mothers with gestational diabetes are at increased risk of giving birth by caesarean section. A standardised assessment method may help to guide in recommendations in planning caesarean birth. We analysed 203 women with gestational diabetes managed in a single centre and developed an aggregate heuri...

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Autores principales: Lu, Huiqi, Hirst, Jane, Yang, Jenny, Mackillop, Lucy, Clifton, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928011/
https://www.ncbi.nlm.nih.gov/pubmed/35340404
http://dx.doi.org/10.1049/htl2.12022
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author Lu, Huiqi
Hirst, Jane
Yang, Jenny
Mackillop, Lucy
Clifton, David
author_facet Lu, Huiqi
Hirst, Jane
Yang, Jenny
Mackillop, Lucy
Clifton, David
author_sort Lu, Huiqi
collection PubMed
description Mothers with gestational diabetes are at increased risk of giving birth by caesarean section. A standardised assessment method may help to guide in recommendations in planning caesarean birth. We analysed 203 women with gestational diabetes managed in a single centre and developed an aggregate heuristic risk score. Among 155 women who had not had a previous caesarean birth, five risk factors (previous birth, weight gain during pregnancy, mother's height, and glycated haemoglobin and fasting blood glucose results at the beginning of pregnancy) were found associated with primary caesarean birth. Risk of primary caesarean birth in low‐risk women (score 0–1) was 13.8%, medium‐risk (score 2–3) 24.5% and high risk (score ≥ 4) 66.7%. The area under the receiver operating characteristic (AUROC) for primary caesarean birth prediction is 0.726 ± 0.003. Machine learning models were then deployed on 97 patients to explore the role of temporal blood glucose in predicting caesarean birth, achieving an AUROC of 0.857 ± 0.008. In conclusion, Oxford caesarean prediction score could help clinicians counselling women with gestational diabetes about their individual risk of primary caesarean birth. Temporal blood glucose measurements may improve the prediction subject to further validation.
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spelling pubmed-89280112022-03-24 Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes Lu, Huiqi Hirst, Jane Yang, Jenny Mackillop, Lucy Clifton, David Healthc Technol Lett Original Research Papers Mothers with gestational diabetes are at increased risk of giving birth by caesarean section. A standardised assessment method may help to guide in recommendations in planning caesarean birth. We analysed 203 women with gestational diabetes managed in a single centre and developed an aggregate heuristic risk score. Among 155 women who had not had a previous caesarean birth, five risk factors (previous birth, weight gain during pregnancy, mother's height, and glycated haemoglobin and fasting blood glucose results at the beginning of pregnancy) were found associated with primary caesarean birth. Risk of primary caesarean birth in low‐risk women (score 0–1) was 13.8%, medium‐risk (score 2–3) 24.5% and high risk (score ≥ 4) 66.7%. The area under the receiver operating characteristic (AUROC) for primary caesarean birth prediction is 0.726 ± 0.003. Machine learning models were then deployed on 97 patients to explore the role of temporal blood glucose in predicting caesarean birth, achieving an AUROC of 0.857 ± 0.008. In conclusion, Oxford caesarean prediction score could help clinicians counselling women with gestational diabetes about their individual risk of primary caesarean birth. Temporal blood glucose measurements may improve the prediction subject to further validation. John Wiley and Sons Inc. 2022-03-13 /pmc/articles/PMC8928011/ /pubmed/35340404 http://dx.doi.org/10.1049/htl2.12022 Text en © 2022 The Authors. Healthcare Technology Letters published by John Wiley & Sons Ltd on behalf of The Institution of Engineering and Technology https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Papers
Lu, Huiqi
Hirst, Jane
Yang, Jenny
Mackillop, Lucy
Clifton, David
Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title_full Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title_fullStr Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title_full_unstemmed Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title_short Standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
title_sort standardising the assessment of caesarean birth using an oxford caesarean prediction score for mothers with gestational diabetes
topic Original Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928011/
https://www.ncbi.nlm.nih.gov/pubmed/35340404
http://dx.doi.org/10.1049/htl2.12022
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