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Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

Obesity leads to the development of nonalcoholic fatty liver disease (NAFLD) and associated alterations to the plasma proteome. To elucidate the underlying changes associated with obesity, we performed liquid chromatography–tandem mass spectrometry in the liver and plasma of obese leptin-deficient o...

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Detalles Bibliográficos
Autores principales: Stocks, Ben, Gonzalez-Franquesa, Alba, Borg, Melissa L., Björnholm, Marie, Niu, Lili, Zierath, Juleen R., Deshmukh, Atul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928073/
https://www.ncbi.nlm.nih.gov/pubmed/35093608
http://dx.doi.org/10.1016/j.mcpro.2022.100207