Enhancing the bioaccessibility of lycopene from tomato processing byproducts via supercritical carbon dioxide extraction

Tomato peel and seed from tomato processing industry are treated as waste; however, they contain lycopene, a high-value bioactive compound. In this study, lycopene was extracted from tomato peel and seed using supercritical carbon dioxide (SC–CO(2)) and hexane, and the bioaccessibilities of lycopene in the SC-CO(2)- and hexane-extracted oleoresins were investigated for the first time. The (Z)-lycopene content of the SC-CO(2)-extracted oleoresin (69%) was higher than that of hexane-extracted oleoresin (45%). Separation of the insoluble fraction from the oleoresins increased the (Z)-lycopene contents of the SC-CO(2)- and hexane-extracted oil fractions to 80% and 49%, respectively. The bioaccessibility of total-lycopene in the oleoresins was increased by 3.3-fold via SC-CO(2) extraction, which was attributed to higher (Z)-lycopene content, and small-sized uniform distribution of lycopene in the oleoresin. SC-CO(2) extraction is not only a green method for extraction of bioactive compounds, but also has the potential to improve health benefits of bioactive compounds.