The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation

Integrins and discoidin domain receptors (DDRs) 1 and 2 promote cell adhesion and migration on both fibrillar and non fibrillar collagens. Collagen I contains DDR and integrin selective binding motifs; however, the relative contribution of these two receptors in regulating cell migration is unclear....

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Detalles Bibliográficos
Autores principales: Borza, Corina M., Bolas, Gema, Zhang, Xiuqi, Browning Monroe, Mary Beth, Zhang, Ming-Zhi, Meiler, Jens, Skwark, Marcin J., Harris, Raymond C., Lapierre, Lynne A., Goldenring, James R., Hook, Magnus, Rivera, Jose, Brown, Kyle L., Leitinger, Birgit, Tyska, Matthew J., Moser, Markus, Böttcher, Ralph T., Zent, Roy, Pozzi, Ambra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928223/
https://www.ncbi.nlm.nih.gov/pubmed/35309920
http://dx.doi.org/10.3389/fcell.2022.836797

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