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IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

The inhibitory receptor interleukin-1 receptor 8 (IL-1R8) has been recently recognized to be expressed also by human natural killer (NK) cells. This study was aimed to design and optimize IL-1R8 silencing conditions in human NK cells to precisely establish the activity of such receptor in these cell...

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Detalles Bibliográficos
Autores principales: Landolina, Nadine, Mariotti, Francesca Romana, Ingegnere, Tiziano, Alicata, Claudia, Ricci, Biancamaria, Pelosi, Andrea, Veneziani, Irene, Azzarone, Bruno Giuseppe, Garlanda, Cecilia, Mantovani, Alberto, Moretta, Lorenzo, Maggi, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928329/
https://www.ncbi.nlm.nih.gov/pubmed/35292515
http://dx.doi.org/10.1136/jitc-2021-003858