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Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells

INTRODUCTION: Plasmacytoid dendritic cells (pDCs) are the main producers of type I interferon (IFN) in SLE. pDCs express high secretory carrier membrane protein 5 (SCAMP5). Recent work in transfected HEK cells connects SCAMP5 to the type I IFN secretory pathway. To further study the role of SCAMP5 i...

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Detalles Bibliográficos
Autores principales: Pouw, Juliëtte N, Olde Nordkamp, Michel A M, O'Toole, Tom G, Radstake, Timothy R D J, Leijten, Emmerik F A, Boes, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928376/
https://www.ncbi.nlm.nih.gov/pubmed/35296555
http://dx.doi.org/10.1136/lupus-2022-000680