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Getting to the (germinal) center of humoral immune responses to SARS-CoV-2

Long-term protection against SARS-CoV-2 requires effective and durable immunity. In this issue of Cell, two papers closely examine germinal centers, the physiological birthplace of adaptive immunity, to quantify the specificity, breadth, magnitude, and persistence of systemic and local humoral immun...

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Detalles Bibliográficos
Autores principales: Tangye, Stuart G., Burnett, Deborah L., Bull, Rowena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928419/
https://www.ncbi.nlm.nih.gov/pubmed/35303427
http://dx.doi.org/10.1016/j.cell.2022.02.018
Descripción
Sumario:Long-term protection against SARS-CoV-2 requires effective and durable immunity. In this issue of Cell, two papers closely examine germinal centers, the physiological birthplace of adaptive immunity, to quantify the specificity, breadth, magnitude, and persistence of systemic and local humoral immune responses following natural infection with, or vaccination against, SARS-CoV-2.