Nitrophenyl-Group-Containing Heterocycles. I. Synthesis, Characterization, Crystal Structure, Anticancer Activity, and Antioxidant Properties of Some New 5,6,7,8-Tetrahydroisoquinolines Bearing 3(4)-Nitrophenyl Group

[Image: see text] Regioselective cyclocondensation of 2,4-diacetyl-5-hydroxy-5-methyl-3-(3-nitrophenyl/4-nitrophenyl)cyclohexanones 1a,b with cyanothioacetamide afforded the corresponding 7-acetyl-4-cyano-1,6-dimethyl-6-hydroxy-8-(3- and -4-nitrophenyl)-5,6,7,8-tetrahydrosoquinoline-3(2H)-thiones 2a...

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Detalles Bibliográficos
Autores principales: Sayed, Eman M., Hassanien, Reda, Farhan, Nasser, Aly, Hanan F., Mahmoud, Khaled, Mohamed, Shaaban K., Mague, Joel T., Bakhite, Etify A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928486/
https://www.ncbi.nlm.nih.gov/pubmed/35309417
http://dx.doi.org/10.1021/acsomega.1c06994

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