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Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications

[Image: see text] Laser powder bed fusion (L-PBF) was attempted here to additively manufacture a new generation orthopedic β titanium alloy Ti–35Nb–7Zr–5Ta toward engineering patient-specific implants. Parts were fabricated using four different values of energy density (ED) input ranging from 46.6 t...

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Autores principales: Nadammal, Naresh, Rajput, Monika, Gupta, Saurabh Kumar, Ivanov, Eugene, Reddy, Anigani Sudarshan, Suwas, Satyam, Chatterjee, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928530/
https://www.ncbi.nlm.nih.gov/pubmed/35309459
http://dx.doi.org/10.1021/acsomega.1c06261
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author Nadammal, Naresh
Rajput, Monika
Gupta, Saurabh Kumar
Ivanov, Eugene
Reddy, Anigani Sudarshan
Suwas, Satyam
Chatterjee, Kaushik
author_facet Nadammal, Naresh
Rajput, Monika
Gupta, Saurabh Kumar
Ivanov, Eugene
Reddy, Anigani Sudarshan
Suwas, Satyam
Chatterjee, Kaushik
author_sort Nadammal, Naresh
collection PubMed
description [Image: see text] Laser powder bed fusion (L-PBF) was attempted here to additively manufacture a new generation orthopedic β titanium alloy Ti–35Nb–7Zr–5Ta toward engineering patient-specific implants. Parts were fabricated using four different values of energy density (ED) input ranging from 46.6 to 54.8 J/mm(3) through predefined laser beam parameters from prealloyed powders. All the conditions yielded parts of >98.5% of theoretical density. X-ray microcomputed tomography analyses of the fabricated parts revealed minimal imperfections with enhanced densification at a higher ED input. X-ray diffraction analysis indicated a marginally larger d-spacing and tensile residual stress at the highest ED input that is ascribed to the steeper temperature gradients. Cellular to columnar dendritic transformation was observed at the highest ED along with an increase in the size of the solidified features indicating the synergetic effects of the temperature gradient and solidification growth rate. Density measurements indicated ≈99.5% theoretical density achieved for an ED of 50.0 J/mm(3). The maximum tensile strength of ≈660 MPa was obtained at an ED of 54.8 J/mm(3) through the formation of the columnar dendritic substructure. High ductility ranging from 25 to 30% was observed in all the fabricated parts irrespective of ED. The assessment of cytocompatibility in vitro indicated good attachment and proliferation of osteoblasts on the fabricated samples that were similar to the cell response on commercially pure titanium, confirming the potential of the additively manufactured Ti–35Nb–7Zr–5Ta as a suitable material for biomedical applications. Taken together, these results demonstrate the feasibility of L-PBF of Ti–35Nb–7Zr–5Ta for potentially engineering patient-specific orthopedic implants.
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spelling pubmed-89285302022-03-18 Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications Nadammal, Naresh Rajput, Monika Gupta, Saurabh Kumar Ivanov, Eugene Reddy, Anigani Sudarshan Suwas, Satyam Chatterjee, Kaushik ACS Omega [Image: see text] Laser powder bed fusion (L-PBF) was attempted here to additively manufacture a new generation orthopedic β titanium alloy Ti–35Nb–7Zr–5Ta toward engineering patient-specific implants. Parts were fabricated using four different values of energy density (ED) input ranging from 46.6 to 54.8 J/mm(3) through predefined laser beam parameters from prealloyed powders. All the conditions yielded parts of >98.5% of theoretical density. X-ray microcomputed tomography analyses of the fabricated parts revealed minimal imperfections with enhanced densification at a higher ED input. X-ray diffraction analysis indicated a marginally larger d-spacing and tensile residual stress at the highest ED input that is ascribed to the steeper temperature gradients. Cellular to columnar dendritic transformation was observed at the highest ED along with an increase in the size of the solidified features indicating the synergetic effects of the temperature gradient and solidification growth rate. Density measurements indicated ≈99.5% theoretical density achieved for an ED of 50.0 J/mm(3). The maximum tensile strength of ≈660 MPa was obtained at an ED of 54.8 J/mm(3) through the formation of the columnar dendritic substructure. High ductility ranging from 25 to 30% was observed in all the fabricated parts irrespective of ED. The assessment of cytocompatibility in vitro indicated good attachment and proliferation of osteoblasts on the fabricated samples that were similar to the cell response on commercially pure titanium, confirming the potential of the additively manufactured Ti–35Nb–7Zr–5Ta as a suitable material for biomedical applications. Taken together, these results demonstrate the feasibility of L-PBF of Ti–35Nb–7Zr–5Ta for potentially engineering patient-specific orthopedic implants. American Chemical Society 2022-03-01 /pmc/articles/PMC8928530/ /pubmed/35309459 http://dx.doi.org/10.1021/acsomega.1c06261 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Nadammal, Naresh
Rajput, Monika
Gupta, Saurabh Kumar
Ivanov, Eugene
Reddy, Anigani Sudarshan
Suwas, Satyam
Chatterjee, Kaushik
Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title_full Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title_fullStr Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title_full_unstemmed Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title_short Laser Powder Bed Fusion Additive Manufacturing of a Low-Modulus Ti–35Nb–7Zr–5Ta Alloy for Orthopedic Applications
title_sort laser powder bed fusion additive manufacturing of a low-modulus ti–35nb–7zr–5ta alloy for orthopedic applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928530/
https://www.ncbi.nlm.nih.gov/pubmed/35309459
http://dx.doi.org/10.1021/acsomega.1c06261
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