Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst

[Image: see text] The data suggests that Na(2) eosin Y-derived photoinduced states act as a HAT catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones in ethanol at room temperature. This research establishes a novel function for using a nonmetallic natural dye, Na(2) eosin Y, availa...

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Autor principal: Mohamadpour, Farzaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928547/
https://www.ncbi.nlm.nih.gov/pubmed/35309418
http://dx.doi.org/10.1021/acsomega.1c05808
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author Mohamadpour, Farzaneh
author_facet Mohamadpour, Farzaneh
author_sort Mohamadpour, Farzaneh
collection PubMed
description [Image: see text] The data suggests that Na(2) eosin Y-derived photoinduced states act as a HAT catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones in ethanol at room temperature. This research establishes a novel function for using a nonmetallic natural dye, Na(2) eosin Y, available commercially and at a cheap cost in the photochemical synthesis using the least amount of catalyst, obtaining good results, speeding up the process, and achieving a high atom economy. The TON and TOF of 3,4-dihydropyrimidin-2-(1H)-ones/thiones are computed. Furthermore, this cycle runs on the gram scale as well, indicating the possibility of industrial purposes.
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spelling pubmed-89285472022-03-18 Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst Mohamadpour, Farzaneh ACS Omega [Image: see text] The data suggests that Na(2) eosin Y-derived photoinduced states act as a HAT catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones in ethanol at room temperature. This research establishes a novel function for using a nonmetallic natural dye, Na(2) eosin Y, available commercially and at a cheap cost in the photochemical synthesis using the least amount of catalyst, obtaining good results, speeding up the process, and achieving a high atom economy. The TON and TOF of 3,4-dihydropyrimidin-2-(1H)-ones/thiones are computed. Furthermore, this cycle runs on the gram scale as well, indicating the possibility of industrial purposes. American Chemical Society 2022-03-03 /pmc/articles/PMC8928547/ /pubmed/35309418 http://dx.doi.org/10.1021/acsomega.1c05808 Text en © 2022 The Author. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Mohamadpour, Farzaneh
Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title_full Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title_fullStr Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title_full_unstemmed Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title_short Visible-Light-Induced Radical Condensation Cyclization to Synthesize 3,4-Dihydropyrimidin-2-(1H)-ones/thiones Using Photoexcited Na(2) Eosin Y as a Direct Hydrogen Atom Transfer (HAT) Catalyst
title_sort visible-light-induced radical condensation cyclization to synthesize 3,4-dihydropyrimidin-2-(1h)-ones/thiones using photoexcited na(2) eosin y as a direct hydrogen atom transfer (hat) catalyst
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928547/
https://www.ncbi.nlm.nih.gov/pubmed/35309418
http://dx.doi.org/10.1021/acsomega.1c05808
work_keys_str_mv AT mohamadpourfarzaneh visiblelightinducedradicalcondensationcyclizationtosynthesize34dihydropyrimidin21honesthionesusingphotoexcitedna2eosinyasadirecthydrogenatomtransferhatcatalyst

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