Increased Prostaglandin E2 in Brainstem Respiratory Centers Is Associated With Inhibition of Breathing Movements in Fetal Sheep Exposed to Progressive Systemic Inflammation

BACKGROUND: Preterm newborns commonly experience apnoeas after birth and require respiratory stimulants and support. Antenatal inflammation is a common antecedent of preterm birth and inflammatory mediators, particularly prostaglandin E2 (PGE(2)), are associated with inhibition of vital brainstem re...

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Detalles Bibliográficos
Autores principales: Stojanovska, Vanesa, Atta, John, Kelly, Sharmony B., Zahra, Valerie A., Matthews-Staindl, Eva, Nitsos, Ilias, Moxham, Alison, Pham, Yen, Hooper, Stuart B., Herlenius, Eric, Galinsky, Robert, Polglase, Graeme R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928579/
https://www.ncbi.nlm.nih.gov/pubmed/35309054
http://dx.doi.org/10.3389/fphys.2022.841229

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